{"product_id":"mots-c","title":"MOTS-C","description":"\u003cp\u003e\u003cstrong\u003eMOTS-C\u003c\/strong\u003e is a naturally occurring mitochondrial-derived peptide (MDP) encoded within the 12S ribosomal RNA gene of the mitochondrial genome, consisting of 16 amino acids. Supplied as a lyophilized powder in a sealed laboratory-grade glass vial. Intended for in-vitro and laboratory research applications only.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Context\u003c\/strong\u003e\u003cbr\u003eMOTS-C is studied in in-vitro and animal-model research into AMP-activated protein kinase (AMPK) signalling, a pathway central to cellular energy homeostasis. In research models it has been observed to translocate to the nucleus under metabolic-stress conditions, making it a subject of interest for investigating nuclear gene-expression and adaptive stress-response pathways. Its association with the folate cycle and de novo purine synthesis, AICAR accumulation, and subsequent AMPK activation is examined in research contexts alongside glucose-uptake, insulin-signalling, and mitochondrial-biogenesis pathways. This mitochondria-to-nucleus signalling profile makes it a subject of interest in metabolic-pathway, insulin-signalling, and cellular-longevity research.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSpecifications\u003c\/strong\u003e\u003cbr\u003e• Sequence: Validated by mass spectrometry (MS\/MS)\u003cbr\u003e• Purity: ≥ 99% by HPLC\u003cbr\u003e• Form: Lyophilized powder\u003cbr\u003e• Molecular Weight: 2,174.4 Da\u003cbr\u003e• Storage: 2 – 8 °C, keep dry and away from light\u003cbr\u003e• Shelf Life: 24 months from manufacture date (sealed)\u003cbr\u003e\u003cstrong\u003e\u003cbr\u003eQuality \u0026amp; Testing\u003c\/strong\u003e\u003cbr\u003eEvery batch is independently tested by a certified third-party laboratory. A Certificate of Analysis (CoA) confirming purity and identity is available for each batch.\u003c\/p\u003e","brand":"Nordpeptid","offers":[{"title":"Default Title","offer_id":58205020488015,"sku":null,"price":34.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1026\/6751\/8287\/files\/Gemini_Generated_Image_jwr4t7jwr4t7jwr4.png?v=1783810513","url":"https:\/\/nordpeptid.de\/en\/products\/mots-c","provider":"Nordpeptid","version":"1.0","type":"link"}